ea0094op2.3 | Metabolism, Obesity and Diabetes | SFEBES2023
Abha Abha
, Zou Zhiyong
, Christian Mark
, Heazell Alexander E.P.
, Saravanan Ponnusamy
, Adaikalakoteswari Antonysunil
Background: Maternal B12 deficiency is linked with adverse metabolic disorders in infants. B12 has a potential epigenetic role which could influence placental dysfunction and fetal metabolism. Adipokines such as leptin and adiponectin play a major role in placental development by regulating lipid metabolism. Alterations in in-utero programming develop risk to obesity and metabolic diseases in offspring. B12 deficiency in mothers has been linked with higher cor...